1. N. Hegazy, K. K. Peng, P. M. D’Aoust, L. Pisharody, E. Mercier, N. T. Ramsay, P. Kabir, T. B. Nguyen, E. Tomalty, F. Addo, C. H. Wong, S. Wan, J. Hu, C. Dean, M. I. Yang, H. Dhiyebi, E. A. Edwards, M. R. Servos, G. Ybazeta, M. Habash, L. Goodridge, A. F. Y. Poon, E. J. Arts, S. Brown, S.J. Payne, A. Kirkwood, D. B. D. Simmons, J.-P. Desaulniers, B. Ormeci, C. Kyle, D. Bulir, T. Charles, R. M. McKay, K. A. Gilbride, C. J. Oswald, H. Peng, C. DeGroot, WSI Consortium, E. Renouf and Robert Delatolla. “Variability of Clinical Metrics in Small Population Communities Drive Perceived Wastewater and Environmental Surveillance Data Quality: Ontario, Canada-Wide Study” ACS Environmental Science & Technology Water, 2025, in press.

2. W. Obrom, W. Yingyuen, T. Nanmong, K. Deekamwong, P. Tawachkultanadilok, J. Wittayakun, S. Prayoonpokarac, Y. Poo-arporn, K. Föttinger, J.-P. Desaulniers and S. Loiha. “Investigating the role of zeolite supports in Ni-based catalysts for CO2-methanation using in situ/operando XAS–GC-MS” Microporous and Mesoporous Materials, 2025, 390, 113548.

3. A. Collins, S. Varley, T. Clark, N. Chubb, S. Forrester and J.-P. Desaulniers. “Increased activity of CF3-derivatised levamisole at the ACC-2 receptor from the parasitic nematode Haemonchus contortus“ International Journal for Parisitology: Drugs and Drug Resistance, 2025, in press.

4. T. De Melo, A. Gedge, D. Simmons, J.-P. Desaulniers and A. Kirkwood. “Optimizing RT-qPCR multiplex assays for simultaneous detection of enteric and respiratory viruses in wastewater“ Journal of Water and Health, 2025, revisions requested.

5. M. Mateus, M. L. Hammill, D. B. D. Simmons and J.-P. Desaulniers. “Injection of Ortho-Functionalized Tetrafluorinated Azobenzene-Containing siRNAs into Japanese Medaka Embryos for Photocontrolled Gene Silencing” Current Protocols in Molecular Biology 2024, 11, e70051.

6. M. Mateus, M. L. Hammill, D. B. D. Simmons and J.-P. Desaulniers. “In vivo Injection of Reversible Optically Controlled Short Interfering RNA into Japanese Medaka Embryos (Oryzias latipes) to Regulate Gene Silencing” ACS Chemical Biology, 2024, 19, 1904-1909.

7. G. Islam, A. Gedge, R. Ibrahim, T. de Melo, L. Lara-Jacobo, T. Dlugosz, A. E. Kirkwood, D. Simmons and J.-P. Desaulniers. “The role of catchment population size, data normalization, and chronology of public health interventions on wastewater-based COVID-19 viral trends” Science of the Total Environment, 2024, 173272.

8. P. M. D’Aoust, N. Hegazy, N. T. Ramsay, M. I. Yang, H. A. Dhiyebi , E. Edwards, M. R. Servos, G. Ybazeta, M. Habash, L. Goodridge, A. Poon, E. Arts, R. S. Brown, S. J.Payne, A. Kirkwood, D. Simmons, J.-P. Desaulniers, B. Ormeci, C. Kyle, D. Bulir, T. Charles, R. M. McKay, K. Gilbride, C. Oswald, H. Peng, V. Pileggi, M. L. Wang, A. Tong, D. Orellano, C. T. DeGroot and R. Delatolla. “SARS-CoV-2 viral titer measurements in Ontario, Canada wastewaters throughout the COVID-19 pandemic” Scientific Data, 2024, 11, 656.

9. I. Giorgees, V. Affe, I. Williams and J.-P. Desaulniers. “Direct Conjugation of Gallium-(III)-Corroles to short interfering RNA(siRNA) Providing Real-Time siRNA Imaging and Gene Silencing" ChemPlusChem, 2024, e202400084 ** selected for front cover art **.

10. T. De Melo, G. Islam, D. B. D. Simmons, J.-P. Desaulniers and A. E. Kirkwood. “Alternative method for monitoring and interpretation of influenza A in communities using wastewater surveillance” Frontiers in Public Health, 2023, 11, 1141136.

11. L. Salim and J-P. Desaulniers. “Synthesis of Folate-Labeled siRNAs From a Folate Derivative Phosphoramidite” Organic & Biomolecular Chemistry, 2023, 21, 3365-3372. ** selected for front cover art **

12. C. Fernandez, I. Giorgees, E. Goss, and J-P. Desaulniers. “Effective Carrier-Free Gene-Silencing Activity of Sphingosine-Modified siRNAs” Organic & Biomolecular Chemistry, 2023, 21, 2107-2117. ** selected for front cover art **

13. M. L. Hammill, K. Tsubaki, M. Kitamura, T. Okauchi, and J.-P. Desaulniers. "Synthesis of an Ortho‐Functionalized Tetrafluorinated Azobenzene Phosphoramidite for Incorporation Into a Tetrafluorinated Azobenzene-Containing siRNA for Photocontrolled Gene Silencing" Current Protocols in Nucleic Acid Chemistry, 2023, 3, e874.

14. J.-P. Desaulniers, K. Tsubaki, M. L. Hammill, M. Kitamura, and T. Okauchi. "Synthesis of Dinucleotide Non-Symmetrical Triester Phosphate Phosphoramidites and their Incorporation within Oligonucleotides " Current Protocols in Nucleic Acid Chemistry, 2023, 3, e784. 

15. A. Varley and J.-P. Desaulniers. "Synthesis of 5’-Fluorophosphate-Modified Short-Interfering RNAs" Nucleosides Nucleotides and Nucleic Acids, 2022, 1-13.

16. M. L. Hammill, K. Tsubaki, Y. Wang, G. Islam, M. Kitamura, T. Okauchi, and J.-P. Desaulniers. "Synthesis, Derivatization and Photochemical Control of an ortho-Functionalized Tetrafluorinated Azobenzene-Modified siRNA" ChemBioChem, 2022, 23, e202200386.

17. M. L. Hammill, G. Islam, and J-P. Desaulniers. “Synthesis of Ortho‐Functionalized Tetrachlorinated Azobenzene Phosphoramidites for Incorporation Into siRNAzos for Photocontrolled Gene Silencing” Current Protocols in Nucleic Acid Chemistry, 2022, e513.

18. M. L. Hammill, K. Tsubaki, L. Salim, A. J. Varley, I. Giorgees, M. Kitamura, T. Okauchi, and J.-P. Desaulniers. "SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity" ACS Medicinal Chemistry Letters, 2022, 13, 695–700.

19. E. Arts, S. Brown, D. Bulir, T. C. Charles, C. T. DeGroot, R. Delatolla, J.-P. Desaulniers, E. A. Edwards, M. Fuzzen, K. Gilbride, J. Gilchrist, L. Goodridge, T. E. Graber, M. Habash, P. Jüni, A. Kirkwood, J. Knockleby, C. Kyle, C. Landgraff, C. Mangat, D. G. Manuel, R. M. McKay, E. Mejia, A. Mloszewska, B. Ormeci, C. Oswald, S. J. Payne, H. Peng, S. Peterson, A. F. Y. Poon, M. R. Servos, D. Simmons, J. Sun, M. Yang, and G. Ybazeta."Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age" 2022, Pre-print, Research Square: 10.21203/rs.3.rs-1439969/v2.

20. L. Lara-Jacobo, G. Islam, J.-P. Desaulniers, A. E. Kirkwood, and D. B. D. Simmons. "Detection of SARS-CoV-2 Proteins in Wastewater Samples by Mass Spectrometry" ACS Environmental Science & Technolology, 2022, 56, 5062–5070.

21. I. Giorgees, F. Wu, Z. Shen, and J.-P. Desaulniers. "A Dual Therapeutic System Based on Corrole-siRNA Conjugates" Organic & Biomolecular Chemistry, 2022, 20, 2626-2635. ** selected for front cover art **

22. G. Islam, A. Gedge, L. Lara-Jacobo, A. Kirkwood, D. Simmons, and J.-P. Desaulniers. "Pasteurization, storage conditions and viral concentration methods influence RT-qPCR detection of SARS-CoV-2 RNA in wastewater" Science of the Total Environment, 2022, 821, 153228.

23. M. L. Hammill, L. Salim, K. Tsubaki, A. Varley, M. Kitamura, T. Okauchi, and J.-P. Desaulniers. "Building siRNAs with Cubes: Synthesis and Evaluation of Cubane-Modified siRNAs" ChemBioChem, 2021, 22, 2981-2985.

24. L. Salim, E. Goss and J.-P. Desaulniers. "Synthesis and Evaluation of Modified siRNA Molecules Containing a Novel Glucose Derivatives" RSC Advances, 2021, 11, 9285–9289.

25. L. Salim and J.-P. Desaulniers. "To Conjugate or to Package? A Look at Targeted siRNA Delivery via Folate Receptors" Nucleic Acid Therapeutics, 2021, 31, 21-38. ** selected for front cover art **

26. A. J. Varley and J.-P. Desaulniers. "Chemical Strategies for Strand Selection in Short-Interfering RNAs" RSC Advances, 2021, 11, 2415–2426.

27. M.L. Hammill, G. Islam, and J.-P. Desaulniers. "Controlling Gene-Silencing with Azobenzene-Containing siRNAs (siRNAzos)" Current Protocols in Nucleic Acid Chemistry, 2020, 83, e119.

28. S. Barmaki, A. Ali, J.-P. Desaulniers, and Y. Bolshan. "Bromination of Codeine and its Derivatives: Revisiting a 95-Year Old Process" Tetrahedron Letters, 2020, 61, 152234.

29. K. Tsubaki, M. L. Hammill, A. J. Varley, M. Kitamura, T. Okauchi, and J.-P. Desaulniers. "Synthesis and Evaluation of Neutral Phosphate Triester Backbone-Modified siRNAs" ACS Medicinal Chemistry Letters, 2020, 11, 1457–1462.

30. M. L. Hammill and J.-P. Desaulniers. "Synthesis of Azobenzene Derivative Phosphoramidites For Incorporation into Oligonucleotides" Current Protocols in Nucleic Acid Chemistry, 2020, 81, e107.

31. M. L. Hammill, G. Islam, and J.-P. Desaulniers. "Synthesis, Derivatization and Photochemical control of Ortho-Functionalized Tetrachlorinated Azoben­­­zene-Modified siRNAs"  ChemBioChem, 2020, 21, 2367-2372.

* Highlighted by the Editorial Board of SYNFACTS! *

32. A. Varley, M. L. Hammill, L. Salim, and J.-P. Desaulniers. "Effects of Chemical Modifications on siRNA Strand Selection in Mammalian Cells"  Nucleic Acid Therapeutics, 2020, 30, 229-236.

33. M. L. Hammill, G. Islam, and J.-P. Desaulniers. "Reversible Control of RNA Interference by siRNAzos"  Organic & Biomolecular Chemistry, 2020, 18, 41-46.

34. L. Salim, G. Islam, and J.-P. Desaulniers. "Targeted Delivery and Enhanced Gene-Silencing Activity of Centrally-Modified Folic Acid-siRNA Conjugates"  Nucleic Acids Research, 2020, 48, 75-85.

35.  M. L. Hammill, A. Patel, M. A. Alla, and J.-P. Desaulniers. "Stability and Evaluation of siRNAs Labeled at the Sense Strand with a 3'-Azobenzene Unit"  Bioorganic & Medicinal Chemistry Letters, 2018, 28, 3613-3616.

36. L. Salim, C. McKim, and J.-P. Desaulniers. "Effective Carrier-Free Gene-Silencing Activity of Cholesterol-Modified siRNAs"  RSC Advances, 2018, 8, 22963-22966.

37. M. L. Hammill, C. Isaacs-Trepanier, and J.-P. Desaulniers. "siRNAzos: A New Class of Azobenzene-Containing siRNAs that Can Photochemically Regulate Gene Expression" ChemistrySelect, 2017, 2, 9810-9814.

38. S. G. Forrester, J. Foster, S. Robert, L. Salim, and J.-P. Desaulniers. "Efficient Synthesis of the GABAA Receptor Agonist trans-4-Aminocrotonic Acid (TACA)" Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4512-4513.

39. J.-P. Desaulniers, G. Hagen, J. Anderson, C. McKim, and B. Roberts. "Effective Gene-Silencing of siRNAs that Contain Functionalized Spacer Linkages Within the Central Region"  RSC Advances, 2017, 7, 3450-3454.

40. G. Hagen, B. J. Peel, J. Samis, and J.-P. Desaulniers. "Synthesis and Biological Assessment of Chemically Modified siRNAs Containing 2'-Ribose Modifications with Triazole-Linked Backbone Modifications" MedChemComm, 2015, 6, 1210-1215.

41. M. Kaji, M. Callanan, A. Kwaka, H. Nusrat, J.-P. Desaulniers, and S. G. Forrester. "A Molecular Characterization of the Agonist Binding Site of a Nematode cys-loop GABA Receptor" British Journal of Pharmacology, 2015, 172, 3737-3747.

42. B. J. Peel, G. Hagen, K. Krishnamurthy, and J.-P. Desaulniers. "Conjugation and Evaluation of Small Hydrophobic Molecules to Triazole-Linked siRNAs" ACS Medicinal Chemistry Letters, 2015, 6, 117-122.

43. J. L. Comstock, J.-P. Desaulniers, H. N. LeBlanc, and S. L. Forbes. "New decomposition stages to describe scenarios involving the partial and complete exclusion of insects" Canadian Society of Forensic Sciences Journal, 2015, 48, 1-19.

44. S. Stadler, J.-P. Desaulniers, and S. L. Forbes. "Inter-year repeatability study of volatile organic compounds from surface decomposition of human analogues." International Journal of Legal Medicine, 2015, 129, 641-650.

45. B. J. Peel, T. C. Efthymiou, and J.-P. Desaulniers. "Synthesis of Triazole-Nucleoside Phosphoramidites and Their Use in Solid-Phase Oligonucleotide Synthesis" Current Protocols in Nucleic Acid Chemistry, 2013, 55:4.57.1-4.57.38.

46. T.C. Efthymiou, W. Gong, and J.-P. Desaulniers. "Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized Via Click Chemistry" Molecules, 2012, 17, 12665-12703.

47. W. Gong and J.-P. Desaulniers. "Gene-Silencing Properties of siRNAs that Contain Internal Amide-Bond Linkages" Bioorganic & Medicinal Chemistry Letters, 2012, 22, 6934-6937.

48. T.C. Efthymiou, B. Peel, V. Huynh, and J.-P. Desaulniers. "Evaluation of siRNAs that Contain Internal Variable-Length Spacer Linkages" Bioorganic & Medicinal Chemistry Letters, 2012, 22, 5590-5594.

49. W. Gong and J.-P. Desaulniers. "Synthesis and Properties of RNAs that Contain a PNA-RNA Dimer." Nucleosides Nucleotides and Nucleic Acids, 2012, 31, 389-400.

50. T.C. Efthymiou, V. Huynh, J. Oentoro, B. Peel, and J.-P. Desaulniers. "Efficient Synthesis and Cell-Based Silencing Activity of siRNAs that Contain Triazole Backbone Linkages" Bioorganic & Medicinal Chemistry Letters, 2012, 22, 1722-1726.

51. T.C. Efthymiou and J.-P. Desaulniers. "Synthesis and Properties of Oligonucleotides that Contain a Triazole-Linked Nucleic Acid Dimer" Journal of Heterocyclic Chemistry, 2011, 48, 533-539.

52. J.-P. Desaulniers. "Pivaloxymethyl Chloride" e-EROS - Encyclopedia of Reagents for Organic Synthesis, D. Crich, Ed.; Wiley InterScience, Chichester, March 15, 2011; DOI: 10.1002/047084289X.rn01252.

53. T.C. Efthymiou, C. Koehler, and J.-P. Desaulniers. "Disodium-2-carbamoyl-2-cyanoethylene-1,1-dithiolate" e-EROS - Encyclopedia of Reagents for Organic Synthesis, D. Crich, Ed.; Wiley InterScience, Chichester, March 15, 2011; DOI: 10.1002/047084289X.rn01251.

54. T.C. Efthymiou and J.-P. Desaulniers. "3-Chloro-3(Diphenylmethoxy)-1,1,1,5,5,5-Hexamethyltrisiloxane" e-EROS - Encyclopedia of Reagents for Organic Synthesis, D. Crich, Ed.; Wiley InterScience, Chichester, October 15, 2010; DOI: 10.1002/047084289X.rn01127.

55. J.-P. Desaulniers. "Tris(2-Acetoxyethoxy)orthoformate" e-EROS - Encyclopedia of Reagents for Organic Synthesis, D. Crich, Ed.; Wiley InterScience, Chichester, October 15, 2010; DOI: 10.1002/047084289X.rn01126.

56. L. W. Lee, C. E. Taylor, J.-P. Desaulniers, M. Zhang. J. W. Hojfeldt, Q. Pan, and A. K. Mapp. "Inhibition of ErbB2(Her2) Expression with Small Molecule Transcription Factor Mimics" Bioorganic & Medicinal Chemistry Letters, 2009, 19, 6233-6236.

57. R. J. Casey, J.-P. Desaulniers, J. W. Hojfeldt, and A. K. Mapp, "Expanding the Repertoire of Small Molecule Transcriptional Activation Domains" Bioorganic & Medicinal Chemistry, 2009, 17, 1034-43.

58. J.-P. Desaulniers, Y.-C. Chang, S. Abeyguarwardena, R. Aduri, J. SantaLucia Jr, and C. S. Chow. "Pseudouridines in rRNA Helix 69 Play a Role in Loop Stacking Interactions", Organic and Biomolecular Chemistry, 2008, 6, 3892-3895.

59. M. Sumita, J.-P. Desaulniers, Y.-C. Chang, H. M.-P. Chui, L. Clos II, and C. S. Chow. "Effects of Nucleotide Substitution and Modification on the Stability and Structure of Helix 69 from 28S rRNAs", RNA, 2005, 11, 1420-1429.

60. J.-P. Desaulniers, H. M.-P. Chui, and C. S. Chow. "Solution Conformation of 3-Methyluridine and 3-Methylpseudouridine", Bioorganic & Medicinal Chemistry 2005, 13, 6777-6781.

61. N. Esho, J.-P. Desaulniers, B. Davis, H. M.-P. Chui, M. S. Rao, C. S. Chow, S. Szafert, and R. Dembinski. "NMR conformational Analysis of p-Tolyl Furanopyrimidine 2'-Deoxyribonucleoside and Crystal Structure of its 3',5'-Di-O-acetyl Derivative", Bioorganic & Medicinal Chemistry, 2005, 13, 1231-1238.

62. N. Hamdy, A. S. Goustin, J.-P. Desaulniers, M. Li, C. S. Chow, and A. Al-Katib. "Sheep Red Blood Cells Armed with Anti-CD20 Single-Chain Variable Fragments (scFvs) Fused to a Glycosylphosphatidylinositol (GPI) Anchor: a Strategy to Target CD20-Positive Tumor Cells", J. Immunol. Methods 2005, 297, 109-124.

63. J.-P. Desaulniers, B. Ksebati, and C. S. Chow. "Synthesis of 15N-Enriched Pseudouridine Derivatives", Organic Letters, 2003, 5, 4093-4096.

64. H. M.-P. Chui, J.-P. Desaulniers, S. Scaringe, and C.S. Chow. "Synthesis of Helix 69 of Escherichia coli 23S rRNA Containing its Natural Modified Nucleosides, m3ψ and ψ", Journal of Organic Chemistry, 2002, 67, 8847-